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At the heart of Metabio’s digital ecosystem, e-MetaBio® serves as the central hub that unifies biomedical data across healthcare, research, and biobanking. As a centralized federated solution, it captures and tracks biosample-related data across the entire usage and value chain, linking biosample-derived molecular profiles with clinical outcomes.
At the core of e-MetaBio® lies a commitment to quality management that extends across every dimension of the biomedical data ecosystem. The platform unifies product integrity, operational excellence, security, support, market readiness, and sustainability into a single, adaptable environment.
By consolidating biospecimen data, clinical records, and research outputs into a dynamic data hub, e-MetaBio® eliminates silos and ensures information is accurate, reproducible, and securely preserved. Built on internationally recognized standards and supported by advanced features including AI-driven data curation, IoT-enabled tracking, and dynamic real-time consent the platform streamlines workflows, safeguards compliance, and drives continuous optimization.
This holistic approach empowers organizations to achieve regulatory alignment, enhance stakeholder trust, and maximize the long-term value of biomedical data. More than a system, e-MetaBio® represents a future-ready solution that links sustainability, innovation, and collaboration into a competitive advantage for the evolving biomedical landscape.
Surrounding e-MetaBio® are specialized sub-platforms, each designed to address distinct domains while seamlessly integrating back into the core:
e-MetaHealth® — Patient-centered real-world data capture and dynamic e-consent. e-MetaBank® — Comprehensive biobank management for biospecimen lifecycle and logistics. e-MetaHep® — Standards-based EMR for hospitals and healthcare institutions. e-MetaRes® — Secure research environment for multi-criteria queries, analytics, and protocol annotation.
Together, this ecosystem creates a holistic, multidimensional digital environment that fosters collaboration, accelerates discovery, and maximizes the translational impact of biomedical research.
A research institute expands nutrition studies using its biobank, requiring reliable pre-analytical data from the healthcare provider.
The healthcare provider lacked a database to capture and share pre-analytical workflows with the biobank.
e-MetaBio® acted as a cross-sector interoperable data hub, ensuring seamless data exchange between the healthcare provider and the biobank. It introduced a service layer for advanced queries, clustering, and adoption mechanisms, enabling comprehensive patient and biosample profiling.
Novel biomarker insights: Accounting for errors and in vitro conditions revealed biomarkers linked to enzymatic activity and apoptosis.
Inventory leverage: New preprocessing standards improved biobank utilization and boosted research output.
A cancer institute required structured IT links with multiple clinical practices to collect real-world and patient-pushed data for advanced AI and ML research.
Data silos with unstandardized formats blocked comparison, mining, and insights.
e-MetaBio® acted as a single-source data hub, managing over 1,000 clinical data types within modular databases. It supported clinical, real-world, and patient-reported data while enabling real-time queries and visualization.
Research Acceleration: Faster discovery pipelines supporting clinical policy-making.
Personalization: Data-driven, evidence-based patient treatment plans.
Follow on Datasets: Flexible, harmonized structures supported continuous ROI.
e-MetaBank® is a modular biobank management platform that records, annotates, and preserves biospecimens across their entire lifecycle, from donor consent to research utilization.
e-MetaBank® is a dedicated, advanced platform designed to ensure the integrity, traceability, and scientific value of biospecimens throughout their journey. It functions as a comprehensive biobank management hub, consolidating logistical data, pre-analytical variables, and biospecimen metadata into a unified environment.
The platform ensures complete transparency by tracking every stage, from acceptance and labeling to cryopreservation, analysis, and distribution.
Specialized modules provide depth and flexibility across repository operations: standardized workflows for processing and analyses, detailed acceptance and collection records, longitudinal annotation tools, advanced query and inventory systems, shipment and packaging management, real-time storage monitoring, and GDPR/HIPAA-compliant dynamic consent. Together, these modules guarantee that every sample is characterized, contextualized, and safeguarded under validated protocols.
e-MetaBank®, not only records critical pre-analytical factors such as ischemia times, storage conditions, and donor-related variables, but also directly improves downstream reproducibility. KPI dashboards and real-time analytics empower institutions to monitor performance, optimize operations, and drive continuous improvement. Interoperable with hospital IT systems, LIMS, and research platforms, the system scales seamlessly from small institutional repositories to large, multi-site biobank networks.
With e-MetaBank®, biobanks can record, annotate, and track biospecimens in real time, ensuring full traceability from collection to research.
A Biobank with 40k+ biospecimens sought to expand their services to Pharma by utilizing their state-of-the-art molecular diagnostic laboratory and joining clinical trials and immuno-oncology studies.
Siloed IT systems and manual processes made data sharing and pharma accreditation impossible. Existing infrastructure couldn’t support service provision to external partners.
e-MetaBank® created a centralized, interoperable database for acceptance, collection, logistics, analysis, shipping, querying, and quality. Data from machinery and departments were harmonized via HL7/FHIR standards.
Umbrella System: End-to-end monitoring of processes improved KPIs.
Inventory leverage: Pharma-ready services were audited and refined.
Inventory leverage: GMP and GDP compliance achieved through harmonized systems.
A biobank with more than 6M biosamples collaborated with a cancer research institute aimed at creating biosample collections from clinical trials and sourcing to translational studies.
Datasets remained fragmented, and manual processes blocked cross-departmental data use. Lack of interoperability prevented harmonized workflows, slowing coordination across the research chain.
e-MetaBio® delivered a searchable, harmonized database. It imported on-site system data, standardized to industry data protocols, for consistent cross-system use and advanced analyses.
Timeframe Gains: Trial data collected and distributed with a 15–20% time reduction.
Longitudinal Synchronization: Data tracked and managed in real-time with minimal resources.
e-MetaHep® is a standards-based electronic medical record platform that unifies clinical, diagnostic, and real-world patient data to ensure accuracy, interoperability, and continuous care.
e-MetaHep® represents a comprehensive and secure digital patient chart, providing real-time access to clinical information for authorized users across hospital departments and partner institutions. Its modular design supports every stage of the patient journey. Medications and treatment plans are tracked in detail to enable evidence-based and precision medicine.
Diagnostics and imaging results are structured into interoperable datasets, automating test orders and streamlining reporting. Screening and laboratory results are connected through predefined test panels, real-time interdepartmental communication, and direct integration with laboratory equipment, ensuring accuracy and speed.
This platform enables bridge in-hospital workflows with off-site care and real-world data streams, transforming medical records into engines of continuous, evidence-driven care. Its standards-based architecture aligns with the European Health Data Space (EHDS), allowing cross-border data exchange and compliance with evolving interoperability frameworks. Scalable for both single institutions and large healthcare systems, e-MetaHep® delivers automation, time optimization, and cost efficiency while strengthening governance, trust, and patient outcomes.
The platform consolidates a patient’s medical history, including allergies, immunizations, surgeries, and prior treatments, while enabling the import of records from external healthcare facilities. Tools for off-site patient management extend care beyond hospital walls, supporting real-time monitoring, follow-up, and remote treatment adjustments. This is complemented by real-world data integration, capturing lifestyle and condition-specific information that enriches clinical records with broader patient context.
e-MetaHep® connects hospitals, clinicians, and patients through a standards-based EMR that unifies diagnostics, treatments, and real-world data into one interoperable system.
A healthcare provider serving 1M+ patients sought to strengthen personalized medicine in rare diseases and cancer.
Departments produced fragmented datasets; manual processes prevented data sharing and slowed workflows.
e-MetaHep® established vertical interoperability within the institution. It supported existing IT systems, unified siloed datasets into a secure database, integrated elements into patients’ EHRs, and enabled data mining, without requiring infrastructure changes.
Added value services: e-MetaHep® enabled growth, setting the institution in a position to provide added value services.
Faster care: Medical personnel draw conclusions on patient care faster, and treatment plans are shared within the institution instantly.
Accessibility: Clinical practice data are structured and research-ready, forming a steady connection with research participants.
A hospital sought an automated solution to connect multiple clinical systems and diagnostic devices, eliminating manual entry and ensuring accurate, personalized patient records.
Disparate file formats and siloed systems prevented interoperability, slowing workflows and risking data errors.
e-MetaBio® provided an interoperable integration tool, importing outputs from diagnostic equipment into a harmonized HL7/FHIR-based database. Results were automatically processed, stored, and converted into personalized EHRs.
Time Savings: Faster result processing and reduced human error.
Unified Oversight: Centralized monitoring of systems and workflows improved hospital KPIs.
Future Research: Longitudinal datasets supported ongoing clinical research and personalized treatment strategies.
e-MetaHealth® is a modular, patient-centered platform that integrates lifestyle, clinical, genealogical, psychological, and physical data into a unified, disease-specific framework for care and research.
e-MetaHealth® is a modular, patient-centered platform that empowers individuals to actively manage their health while contributing real-world data to the biomedical research ecosystem. By capturing lifestyle, clinical, genealogical, psychological, and physical information within a disease-specific framework, it creates a holistic and dynamic portrait of each patient.
This platform embeds Dynamic Real-Time Tiered e-Consent, ensuring patients retain full control over their data with GDPR/HIPAA-compliant governance. Consent can be adjusted or revoked at anytime, with updates reflected instantly across all stakeholders, reinforcing transparency and trust.
Specialized modules provide depth and precision: demographics capture personal and social context; clinical records securely connect admissions, diagnostics, and laboratory results; genealogy maps hereditary risks; “My Health” consolidates diagnoses, vital signs, allergies, and hospitalizations; lifestyle modules track daily habits and environmental factors; psychology records emotional and mental health states; and physical modules document anthropometrics, pain levels, and usability metrics. Together, these create a comprehensive, contextualized dataset that supports both individual care and broader scientific insights.
Designed for interoperability, e-MetaHealth® integrates seamlessly with hospital IT systems, registries, and research infrastructures. Patient-reported outcomes and clinical data flow into advanced analytics and visualization tools that help providers identify trends, improve decision-making, and deliver precision care. For researchers, the platform transforms fragmented patient inputs into structured, high-value datasets that accelerate discovery and strengthen longitudinal studies.
e-MetaHealth® represents a patient-centered approach that transforms real-world data into actionable insights, empowering individuals, supporting providers, and accelerating research for better health outcomes.
A European consortium required patient-driven data (from labs, clinical centers, biobanks, and patients across diverse regions) and environmental insights for chronic disease management.
Collecting disease progression data alongside environmental and patient-reported metrics was complex. Limited patient access to clinical centers and budget constraints hindered creation of a robust empowerment platform.
e-MetaHealth® provided a disease-specific, patient-oriented platform where patients could record therapies, symptoms, adverse events, genetic profiles, and lifestyle data. Data connected seamlessly to digital devices.
Participation: Patient involvement increased tenfold.
Trust: Dynamic e-consent built participant confidence.
Extended Research: Larger datasets broadened the disease research spectrum.
A university hospital and research consortium sought to build a longitudinal database for rare metabolic disorders.
Fragmented IT systems and lack of lifestyle, genealogical, and psychosocial data limited disease insights.
e-MetaHealth® created a patient-centered platform where individuals recorded lifestyle, genealogy, and psychological metrics alongside their medical data. Interoperability with hospital IT ensured harmonized records, while dynamic e-consent enabled flexible participation in research.
Dataset Expansion: Enriched with patient-reported outcomes for more comprehensive analysis.
Patient Engagement: Increased participation and trust in research activities.
Disease Insights: Improved understanding of progression and treatment responses.
e-MetaRes® is a research-focused platform that enables accredited institutions to query, analyze, and annotate patient and biosample data within a secure, dynamic environment.
e-MetaRes® is a specialized platform created for researchers and research institutions, providing secure and structured access to patient and biosample data across the system’s network. By combining clinical, laboratory, genealogical, lifestyle, and biospecimen information, the platform enables researchers to perform precise multi-criteria queries that generate highly refined patient cohorts tailored to their study needs.
Complementing these features, GDPR/HIPAA-compliant dynamic consent ensures ethical access to biospecimens and data, enabling transparent recruitment and responsible collaboration across global networks.
With the involvement of uniting multi-source data, advanced analytics, and interoperable workflows, e-MetaRes® transforms dispersed patient and biosample information into actionable insights. It accelerates cohort discovery, strengthens precision medicine research, and fosters cross-disciplinary collaboration. In doing so, e-MetaRes® empowers the research community with a scalable, transparent, and future-ready platform designed to drive innovation in biomedical science.
e-MetaRes® functions as a dynamic research hub. It integrates real-time analytics, a universal dashboard for population-level insights, and a user-friendly environment that supports hypothesis-driven exploration without requiring advanced IT expertise. Researchers can revisit stored search histories, annotate protocols from a library of thousands of assays, and generate reproducible workflows that streamline both design and execution.
With e-MetaRes®, researchers can query, analyze, and annotate patient and biosample data in real time, accelerating discovery while ensuring reproducibility, transparency, and compliance.
A Pharma-Research entity received a cohort of 100,000 donor records from a Biobank to accelerate target identification. Researchers needed to run multicriteria queries and refine cohorts.
Extracting value required standardized, harmonized datasets. On-site capabilities were insufficient, forcing reliance on partial, low-ROI data unless a new solution was found.
e-MetaBio® integrated cohort data into its platform, ontologically unifying it via HL7, SNOMED, and LOINC standards. This created harmonized, analysis-ready datasets available through e-MetaRes.
Unbiased cohort studies: Accurate queries and refined study cohorts.
Time Savings: 70% faster transition from sourcing to usable datasets.
Follow on Dataset Releases: Continuous ROI through new data integration.
A Translational Research group aimed to identify biosamples tailored to specific biomarker discovery needs across multiple biobank repositories.
Quality indicators are not often recorded for pre-analytical handling and storage conditions. Variability in practices affects the downstream applications.
e-MetaRes® enabled researchers to search federated biobank collections and automatically rank high-quality, fit-for-purpose biosamples using percentage-based cluster adoption.
Precision Matching: Researchers obtained study-specific biosamples.
Quality Assurance: Analytics ensured biosample suitability before acquisition.
Research Efficiency: Quicker, reliable biosample selection minimized delays.
e-Embryo® is a lifelong digital health record, capturing maternal, fetal, and child data from conception to adulthood within one secure, dynamic e-booklet.
e-Embryo® is an innovative e-diary and e-booklet platform designed to capture and preserve the health record of every child, beginning at conception and extending through all stages of development. By documenting maternal health, fetal milestones, and pediatric data in a single lifelong record, it creates a comprehensive, dynamic, and contextualized profile of child well-being.
For parents, e-Embryo® functions as an accessible health companion and educational resource, empowering them with timely information and transparent data governance. In critical situations, such as emergencies or high-risk pregnancies, the platform acts as a lifeline, giving clinicians instant access to a child’s comprehensive medical history and test results, enabling fast and informed decisions.
For healthcare professionals, including obstetrician-gynecologists and pediatricians, e-Embryo® provides real-time updates and longitudinal insights across maternal and child health. Its integration with existing healthcare systems ensures interoperability, while its GDPR-compliant dynamic e-consent framework guarantees that families remain in full control of how their sensitive data is shared, accessed, and used.
During pregnancy e-Embryo® records vital details such as clinical milestones, screenings, laboratory results, and maternal habits. This data is complemented by fetal diagnostics and monitoring, ensuring early identification of potential risks. Following birth, the record evolves with the child, tracking physical growth, immunizations, hospitalizations, cognitive progress, and psychomotor development. Each achievement is documented, creating a trusted roadmap that supports prevention and nurtures potential.
e-Embryo® follows every stage of life, from pregnancy to childhood, uniting health data into one trusted record that empowers families and guides clinicians.
Expecting parents with a history of gestational complications wanted to ensure continuous monitoring and early detection of potential risks during pregnancy.
Frequent visits and scattered records across multiple providers made it difficult to track maternal and fetal health data in real time.
e-Embryo® provided a comprehensive e-diary that integrated maternal health data, fetal diagnostics, and lifestyle tracking, while obstetricians accessed real-time updates through the platform, enabling personalized care throughout the pregnancy.
Timely Interventions: Early detection of potential complications reduced risk for both mother and child.
Parental Confidence: Continuous monitoring increased trust and reduced anxiety.
Comprehensive Record: All data were securely stored and easily shared with medical staff as needed.
Parents of a newborn with a congenital condition needed to coordinate care across multiple pediatric specialists and track the child’s development.
Medical records were scattered among various hospitals and clinics, making it hard to maintain a complete picture of the child’s health.
e-Embryo® consolidated all prenatal and pediatric records, into a single, secure e-booklet. Parents and clinicians tracked development and therapy progress, while dynamic e-consent allowed controlled data sharing across providers.
Improved Care Coordination: Specialists accessed a unified record, reducing duplicated tests and errors.
Holistic Monitoring: Parents tracked progress in real time and contributed observations.
Empowered Families:Secure data management and e-consent fostered trust and collaboration.
BioLink® is a decentralized marketplace that unites patients, hospitals, biobanks, and researchers through secure, transparent, and patient-centric data transactions.
BioLink®, is an advanced platform that merges distributed ledger technology (DLT) with intelligent tools to transform the way biospecimens, biospecimen-related data, and patient information are exchanged. Built as a dynamic transaction hub, it allows biospecimens, datasets, and services to be securely catalogued, searched, and exchanged within a transparent and trusted digital environment.
Unlike conventional siloed systems, BioLink®, introduces a patient-centric usage chain. Individuals gain real-time control over their biological data and consent preferences, while institutions such as hospitals, biobanks, and research organizations gain powerful tools to manage procurement, logistics, and data utilization. Every user, whether a provider or consumer, interacts through tailored workflows, ensuring that both data exchange and biospecimen transactions are ethical, traceable, and efficient. In addition, integrated real-time messaging fosters direct collaboration, and embedded consent workflows guarantee GDPR/HIPAA-compliant governance with full patient empowerment.
Through this combination of blockchain transparency, patient-driven consent, and streamlined operations, BioLink®, addresses some of the most pressing challenges in biomedical research and biobanking. It enhances trust by making every transaction auditable, reduces costs and administrative burden through automated workflows, and ensures compliance with ethical and regulatory frameworks across multiple jurisdictions.
The platform’s modular capabilities make it a comprehensive solution for the entire ecosystem. A unified dashboard provides seamless access to biospecimens, datasets, services, contracts, and communication channels. A multi-criteria search engine enables precise matching of resources to clinical or research needs. Providers can create and manage products with metadata, consent documentation, and sales tracking, while consumers benefit from intuitive basket and purchasing functions with secure processing.
With BioLink®, every biospecimen and dataset becomes part of a transparent, decentralized marketplace, empowering patients and enabling trusted collaboration across the biomedical community.
A national biobank sought to expand its collaborations with international pharmaceutical companies and academic researchers.
Difficulties showcasing specimen inventory across borders, lack of transparent procurement workflows, inconsistent contract handling, and compliance concerns slowed down potential partnerships.
BioLink® enabled cataloging biospecimens, data and consent records on a decentralized marketplace. Automated contract management and traceable transactions simplified procurement while ensuring compliance with GDPR and international standards.
Global Reach: Expanded collaborations with pharma and research institutions.
Operational Efficiency: Reduced administrative burden with automated order handling and contract workflows.
Trust & Compliance: Blockchain-based traceability reassured partners and ensured full consent compliance.
A kidney cancer patient wished to contribute biosamples and data to support oncology research aimed at developing new treatments.
The patient had little motivation to remain engaged, as they lacked visibility into how their contributions would be used and saw no direct personal benefit.
Through BioLink®, the patient accessed a secure, decentralized marketplace that enabled transparent participation. They could donate biosamples and data in exchange for incentives such as medical services, manage consent dynamically, and track the use of their contributions in real time.
Patient Empowerment: Control over data and biosample usage.
Strengthened Motivation: Transparency and incentives build ongoing engagement.
Accelerated Research:Transparency and trust foster ongoing participation.
DRT e-Consent® is a universal, user-centric platform that transforms static consent into dynamic, real-time data governance, ensuring transparency, compliance, and trust across healthcare, finance, and research.
DRT e-Consent® is a universal and customizable platform that redefines how consent is managed across healthcare, finance, and research. Where outdated paper forms, static templates, and one-time permissions create inefficiencies and compliance risks, DRT e-Consent® introduces a dynamic, adaptable model.
It allows individuals to assign, update, or revoke consent at any time, giving them full control over who can access their data, under what conditions, for what purpose, and for how long. This continuous flexibility ensures that consent remains meaningful, enforceable, and aligned with both personal expectations and institutional requirements.
DRT e-Consent® platform is powered by a Digital Rights Management framework that enforces fine-grained control over data storage, usage, and retention. Changes are automatically propagated across connected systems, ensuring seamless interoperability and eliminating gaps in compliance. Every action is captured in an auditable log, guaranteeing accountability and meeting the strict demands of global regulations such as GDPR and HIPAA. By embedding blockchain-enabled transparency, the platform ensures that all consent decisions are tamper-proof, verifiable, and trusted by individuals and organizations alike.
DRT e-Consent® is designed with accessibility in mind. Its intuitive dashboards allow patients, customers, researchers, and administrators to manage consent without technical expertise, reducing administrative burden and simplifying workflows. For institutions, this translates into lower operational costs, faster data governance processes, and a scalable framework that remains adaptable as regulations evolve.
A user-friendly dashboard where individuals manage consent in real time, adjusting access, purpose, and duration with full transparency and compliance.
A pharmaceutical company was running multi-site clinical trials and needed to manage patient consent across hundreds of participants.
Static, paper-based consents delayed enrollment and updates, with reconfirming consents adding significant time and administrative costs, while increasing compliance risk.
DRT e-Consent® implemented a real-time, tiered consent platform. Participants could dynamically update or revoke consent at any time, while automated workflows ensured all changes were instantly reflected across the trial’s databases and connected biobanks.
Compliance Assurance: Real-time updates ensured adherence to GDPR/HIPAA.
Operational Efficiency: Reduced administrative overhead and enrollment delays.
Patient Empowerment: Participants retained full control over their data throughout the trial.
AA medical research center needed ongoing patient engagement and biosample donation to support research and development activities.
Static paper consents and fragmented systems made it difficult for patients to update their preferences or understand who accessed their data.
DRT e-Consent® provided a real-time, tiered platform that empowers patients to manage who can access their health data, update or revoke consent at any time, with changes reflected instantly across all connected hospital stakeholders.
Patient Control: Patients actively manage data access and sharing.
Trust & Engagement: Transparent consent builds confidence in care and research participation.
Streamlined Care & Research:Real-time updates ensure data is current without administrative delays.
